Uwezo Uplift Foundation was founded in 2006 by its current director, Roselyn Nangila. It started in a German Mission in Kenya known as Die Gute Nachricht fur Africa (DIGUNA), which is a German word meaning the Good News for Africa.

Being familiar with Slum life ,the poor living conditions , terrible decay, cycles of abuse and rejection, gangsterism, violence and crime. Moved by what she had seen and experienced, a fresh vision to see children’s lives transformed filled her. Roselyn began developing what would become the heartbeat of The Uwezo Uplift Foundation. She strove to reach out to the poor children in the slums with the gospel and support them educationally where possible. During this time, she was working in the mission as a volunteer evangelist mostly in schools and later as a radio presenter with Bibilia Husema Station affiliated to DIGUNA.

By the time she started the foundation, she was working at the radio station where she got sh1500(15euros) of pocket money. She set aside sh500(0.5euros) for helping the poor which became the basis for the foundation. She would talk with friends and as time went by, got interested in supporting the poor children within the slum. With this, the foundation grew and it began supporting more slum children in the sponsorship program which had already been established.

It being a sense of urgency to establish her vision, the director resigned as a radio presenter in 2011 to work full time in the foundation. Operational activities had increased as more and more poor children were enrolled in the sponsorship program which created the need for more programs to help the children psychologically, mentally and physically. In 2016, the foundation had attained its significant level of operating on its own hence detached from working under DIGUNA leadership. Officially, the foundation was launched as Uwezo Uplift Foundation from the then DIGUNA Slum Ministry with Diguna leadership still and outstanding partner Ts Care from Germany.